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However, a study among children with epilepsy has shown that leptin levels in children on a ketogenic diet were significantly lower (mean 2.71 ± 0.93 ng/mL) compared to children in the control group (mean 6.14 ± 2.07 ng/mL) (valproic acid (VPA) group: mean 5.85 ± 1.79 ng/mL) [99]

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Professor Alejandra Tomas Catala, lead author and Head of Section of Cell Biology and Functional Genomics in the Department of Metabolism, Digestion and Reproduction, said: “Our study reveals an entirely new way in which GLP-1 receptor agonists protect pancreatic β-cells