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Moreover, either exendin (9–39) or GLP-1R siRNA could not eliminate the metformin-induced upregulation of p-PKA protein level in PA-treated endothelial cells (Supplemental Fig
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Synthesis of disulfide linker functionalized (+)-MK-801 and inactive MK-801 2-Mercaptoethanol (Sigma-Aldrich) was treated with 2,2-dipyridyl disulfide (3 equivalents) (Sigma-Aldrich) in dry methanol for 2 h
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