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DPP-4 inhibitors and GLP-1RAs: cardiovascular safety and benefits - PMC

Compounded semaglutide is a customized version of semaglutide that may contain extra ingredients such as vitamin B6, vitamin B12, or glycine

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While a negative feedback loop has not been identified, the very high levels of these medications not only ‘flood’ the body, but do so for extended periods, unlike endogenous GLP-1, which normally fluctuates in response to eating