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Achievement thresholds at 48 weeks (12 mg dose): ≥5% weight loss: 100% of participants ≥10% weight loss: 93% of participants ≥15% weight loss: 83% of participants ≥20% weight loss: 63% of participants ≥25% weight loss: 48% of participants ≥30% weight loss: 26% of participants Research Evidence The clinical evidence base for retatrutide continues to expand through multiple trials: Phase 2 Obesity Trial (NEJM, 2023): This randomized, double-blind, placebo-controlled trial enrolled 338 adults with obesity

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This FDA-approved therapy is available as both an injection and oral pill, designed to manage chronic weight management by reducing appetite and promoting sustained weight loss through the action of GLP-1, a natural hormone