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Effectiveness for Weight Loss Phentermine: Average weight loss is around 5–10% of body weight GLP-1 medications: Can lead to 10–20% (or more) weight loss in many patients GLP-1s generally produce more significant and sustained results
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Last quarter, the company submitted its drug orforglipron, a new GLP-1 agonist, for obesity treatment in the United States and more than three dozen additional countries, with an expected domestic launch by mid-2026