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Berberine, a natural isoquinoline alkaloid, is increasingly recognized for its therapeutic effects on metabolic disorders, specifically its ability to regulate blood glucose and reduce body weight by influencing glucagon-like peptide-1 (GLP-1) levels (M
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Compared with metformin, hazard ratios for colorectal and gallbladder cancers remained below one, but the differences were not statistically significant (Figure 3)
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